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Image Search Results
Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: CD80/CD86 costimulation regulates acute vascular rejection.
doi: 10.4049/jimmunol.175.9.6197
Figure Lengend Snippet: FIGURE 1. Onset of Ab-driven AVR at POD 5 in the absence of CD80 costimulation and onset of CMR at POD 17 in the absence of CD86 costimulation. A, Pa- thology of heart xenografts. HPS staining of xenograft hearts in CD80/ (POD 5), CD86/ (POD 6 and 17), and WT (POD 6 and 21) recipients. Scale bar, 100 m. Arrows indicate thrombosis and arrowheads hemor- rhage. B–D, Quantitation of serum xenoreactive Abs. Serum mouse anti-rat IgM (B), IgG1 (C), and IgG2a (D) Abs were measured in CD80/ (POD 0 and 5), CD86/ (POD 0, 6, and 17), and WT (POD 0, 6, and 21) recipients by flow cytometry. Data represent mean fluorescent intensity SD (n 4). , p 0.05 vs CD86/ POD 6, , p 0.01 vs CD86/ POD 6. POD 5 is also the endpoint of rejection in CD80/
Article Snippet: Sections were stained using goat anti-mouse IgM or IgG-biotin (Caltag Laboratories), CD4-biotin (YTS 191.1.2; Cedarlane Laboratories), CD8-biotin (53-6.7; BD Biosciences), or
Techniques: Staining, Quantitation Assay, Cytometry
Journal: Journal of immunology (Baltimore, Md. : 1950)
Article Title: CD80/CD86 costimulation regulates acute vascular rejection.
doi: 10.4049/jimmunol.175.9.6197
Figure Lengend Snippet: FIGURE 2. Intragraft IgM and IgG deposition. Enumeration of intragraft IgM (A), and IgG (B) deposition in CD80/ (POD 5), CD86/ (POD 6 and 17), and WT (POD 6 and 21) grafts as measured by immunohisto- chemical staining (n 6). IgM and IgG deposition shown as number of positive cells/20 field SD. , p 0.01 vs CD86/ POD 6. ‡, POD 5 is also the endpoint of rejection in CD80/ mice.
Article Snippet: Sections were stained using goat anti-mouse IgM or IgG-biotin (Caltag Laboratories), CD4-biotin (YTS 191.1.2; Cedarlane Laboratories), CD8-biotin (53-6.7; BD Biosciences), or
Techniques: Staining